Implications for Vaccine Design among Hyperinvasive Meningococci: Distribution of Surface Protein Variants
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منابع مشابه
Distribution of surface protein variants among hyperinvasive meningococci: implications for vaccine design.
The bacterium Neisseria meningitidis is a major cause of meningitis and septicemia worldwide. Outer membrane proteins (OMPs) are candidates in the search for comprehensive meningococcal vaccines; however, the formulation of OMP vaccines is complicated by antigenic diversity, which is generated by high levels of genetic reassortment and strong positive selection in the meningococcal antigen gene...
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